Are my tests conclusive ? Please help

Originally Posted: 
Monday, June 4, 2012
Question: 

 

Hi
 
I have few questions about HIV Testing I had an exposure on
Oct-26,2011 (Received Un-protected Oral). Unknowingly I went for Laser
treatment for acne on face in Dec,2011.
 
Everything was fine. On Mar-21,2012( app after 5months of exposure)
received Herpes Zoster opthalmicus.( Shingles) After that undergone
below tests:
1) Elisa Antibody : Negative On 23th week after exposure.
2) Viral Load Test : <20 copies/ml on 24th week
3) Elisa Antibody : Negative on 26th week
4) AB test + P24 : Negative on 28th week
5) Elisa AB test : On 30th week ( 6 months)
6) DNA PCR Test : HIV-1/2 Not detected ( 7 Months after exposure)
 
Need your suggestion on below questions:
1) Had Laser Radiation treatment which I took for acne's on face has
delayed the Anti-bodies production ?
2) During Shingles, I was on high dosage of Acyclovir(800mg*5 perday
for 12 days)...Does this supress the viral load to undectable level
which Viral load test couldn't recognise ?
3) I heard that Antibody tests are conclusive after 6months...But
still I would like to know, If my anti-bodies  production could have
been delayed, will PCR-DNA test be still accurate after 7months of
exposure (Becoz I came to know RNA test isnt accurate at that time,
does this applicable for DNA as well ?) I have mild joint pains which
resolve by them-selves in few minutes, white coated tongue. I'm
getting all these strange doubts...When I take the test, I will be
fine for few days. then again I feel wierd and want to get tested.
Doctor, Please suggest what can be done after these tests...Are these
tests conclusive ? 
Answer: 

 

Hi there,

Thank you for using AIDS Vancouver as your source for HIV/AIDS related information.

It is important to first note that receiving oral sex is considered a negligible risk activity. Additionally, our saliva actually contains enzymes which kill the virus. In order to contract HIV, the virus needs a fluid, activity, and direct access to the bloodstream.

In your case, there was a negligible risk activity, and no direct access to the bloodstream.

I will answer your  questions below:

1)    Your body starts making antibodies to any virus directly after infection. Thus, if you had been infected with HIV during that first encounter, your body would have already started making antibodies to fight the virus. Laser treatment does not affect antibody production. Based on your timeline it seems like you received laser treatment anywhere after 1 week post-exposure. Thus, your body would have already started producing antibodies. Additionally, you have been tested from 3-6 months post-exposure, during which time you would have built up more than enough antibodies to be detected in the ELISA test.

2)    Shingles is not necessarily a symptom of HIV infection.  It is part of the Herpes family and can be brought on by a variety of factors.  I would highly recommend you discuss this with your Health Care Professional, so that it may be addressed.

3)    The PCR DNA and RNA tests detect the genetic material of HIV itself. In this process, the genetic material of HIV is extracted and amplified, and detected – should HIV exist in your blood. While both these tests are highly accurate (99.9%), they are only available for screening of HIV+ babies or organ donors, in Vancouver. Both tests are accurate and results considered conclusive after 3 months.

The World Health Organization and International Guidelines on HIV testing consider test results accurate after 3 months. Thus, the fact that you have had a variety of tests in a large time frame, all with negative results indicate that you are not HIV positive, and these results are conclusive. Your symptoms may be due to another illness, thus it is best to work with a medical practitioner and have them diagnosed.

We recommend that anyone engaging in sexual activity go for regular STI check ups, to protect themselves and their partners.

I do hope that I have addressed your concerns. If you have any further questions, please feel free to contact us again.

Stay Healthy,
Sasha
AIDS Vancouver Helpline Volunteer
E-mail: helpline@aidsvancouver.org
Phone (Mon-Fri 9-4pm): (604) 696-4666
Web: www.aidsvancouver.org/helpline

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